WATCH: Bill Maher says Vance interview critics wouldn't be happy unless he 'punched him in the nose'

He continued, "I don't play that game. I like to actually talk to people."

Maher faced criticism after Friday's episode of "Real Time with Bill Maher" interviewing Vance as some argued he failed to challenge the vice president aggressively enough on political issues.

The comedian, whose political commentary has often put him at odds with Trump and other Republicans, said his opinion of the vice president didn't change after his interview, as he "talks to these guys all the time," referring to politicians and Republicans. He shared that his conversations with Republicans usually go well.

"Everybody's a monster till you talk to them," he said in reference to his interviews with Republicans.

He continued, "Are there things we're never going to agree on? Yeah."

"They're happy warriors," he said in regards to Vance and other  Republicans he has interviewed. "You hit them with three really, really hard-hitting things that say 'you can't keep doing it,' and they just answer it," Maher said. "They evade it. But they don't hold it against you. It doesn't turn hateful."